Cotrazim Tablets

Indications:-

Cotrazim may be indicated in the treatment of the following infections when caused by susceptible strains of bacteria & there is good reason to prefer this combination to a single antibiotic

Urinary Tract Infections : Acute, recurrent and chronic urinary tract infections due to Escherichia coli, Klebsiella species and Proteus mirabilis and vulgaris.

Genital Tract Infections : Uncomplicated gonococcal urethritis.

Upper and Lower Respiratory Tract Infections : Upper and lower respiratory tract infections due to Streptococcus pyogenes, viridians and pneumoniae, Haemophilus influenzae, as well as Staphylococcus aureus and albus.

Gastrointestinal Tract Infections : Infections due to Salmonella typhi, paratyphi, typhimurium and enteritidis, and Shigella species.

Skin and Soft Tissue Infections : Infections due to Streptococcus pyogenes and viridans, as well as Staphylococcus aureus and albus.

Cotrazim may also be indicated in the treatment and prophylaxis (primary and secondary) of Pneumocystis carinii pneumonia in adults & children over twelve years of age, particularly if they are immuno-suppressed.

Treatment and prophylaxis of toxoplasmosis.

Treatment of nocardia infections.

Appropriate culture and susceptibility studies should be performed. On the basis of clinical judgement and anticipated bacteriological findings, therapy may be instituted before results of susceptibility studies are obtained.

Antibiotic treatment may require modification once these results become available. If there is a failure to respond to therapy with Cotrazim, its administration should be terminated and appropriate alternative therapy instituted.

It should be noted that the effects of combinations of sulphamethoxazole and trimethoprim have not been fully evaluated in streptococcal infections.

• Next >