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Razimectin 3mg Tablets

Indications :-

 

RAZIMECTIN is indicated for the treatment of the following infections ;

·         Strongyloidiasis of the intestinal tract :- RAZIMECTIN is indicated for the treatment of intestinal (i.e. nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis.

This indication is based on clinical studies of both comparative and open-label designs, in which from 64-100% of infected patients were cured following a single 200-mcg/kg dose of ivermectin .

 

·         Onchocerciasis :- RAZIMECTIN is indicated for the treatment of onchocerciasis due to the nematode parasite Onchocerca volvulus.

This indication is based on randomized, double-blind, placebo-controlled and comparative studies conducted in 1427 patients in onchocerciasis-endemic areas of West Africa. The comparative studies used diethylcarbamazine citrate (DEC-C).


NOTE :-  RAZIMECTIN has no activity against adult Onchocerca volvulus parasites. The adult parasites reside in subcutaneous nodules which are infrequently palpable. Surgical excision of these nodules (nodulectomy) may be considered in the management of patients with onchocerciasis, since this procedure will eliminate the microfilariae-producing adult parasites.